Assay Detail
Binding
CHEMBL5503263
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GST-tagged human recombinant VEGFR2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.01 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5559432 | — | — | 1 | 7.12 |
| CHEMBL5558384 | — | — | 1 | 6.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5559432 | — | IC50 | = | 75.0 | nM | 7.12 |
| CHEMBL5558384 | — | IC50 | = | 126.0 | nM | 6.90 |