Assay Detail
Functional
CHEMBL5503264
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.42 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5517680 | — | — | 1 | 8.22 |
| CHEMBL5559432 | — | — | 1 | 5.52 |
| CHEMBL5558384 | — | — | 1 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5517680 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL5559432 | — | IC50 | = | 3020.0 | nM | 5.52 |
| CHEMBL5558384 | — | IC50 | = | 3110.0 | nM | 5.51 |