Assay Detail
Functional
CHEMBL5503265
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Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.30 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5517680 | — | — | 1 | 7.72 |
| CHEMBL5558384 | — | — | 1 | 5.67 |
| CHEMBL5559432 | — | — | 1 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5517680 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL5558384 | — | IC50 | = | 2150.0 | nM | 5.67 |
| CHEMBL5559432 | — | IC50 | = | 3120.0 | nM | 5.51 |