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Assay Detail

CHEMBL5503274

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human HUVEC cells assessed as reduction in cell viability by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type HUVEC
Confidence 1 — Organism
Curated By Autocuration

Target

HUVEC (CHEMBL613979)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Thakur A, Rana M, Mishra A, Kaur C, Pan CH, Nepali K.
Eur J Med Chem (2024) 272 : 116472 -116472
PubMed 38728867 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.10 9.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5549937 1 9.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5549937 IC50 = 0.8 nM 9.10