Assay Detail
Binding
CHEMBL5503276
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of C-RAF (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
RAF proto-oncogene serine/threonine-protein kinase (CHEMBL1906) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.50 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5512465 | — | — | 1 | 7.00 |
| CHEMBL5418423 | — | — | 1 | 6.00 |
| CHEMBL5555499 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5512465 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5418423 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL5555499 | — | IC50 | > | 100000.0 | nM | - |