Assay Detail
Binding
CHEMBL5503628
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Binding affinity to mouse galectin-3 assessed as dissociation constant by competitive fluorescence polarization assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.34 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5512479 | — | — | 1 | 7.47 |
| CHEMBL4297442 | OLITIGALTIN | 2.0 | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5512479 | — | Kd | = | 34.0 | nM | 7.47 |
| CHEMBL4297442 | OLITIGALTIN | Kd | = | 61.0 | nM | 7.21 |