Assay Detail
Binding
CHEMBL5504244
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Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cells assessed as inhibition constant by radioligand competition binding assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Potent, Selective Agonists for the Cannabinoid-like Orphan G Protein-Coupled Receptor GPR18: A Promising Drug Target for Cancer and Immunity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.53 | 5.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5556102 | — | — | 1 | 5.93 |
| CHEMBL5557729 | — | — | 1 | 5.46 |
| CHEMBL5542965 | — | — | 1 | 5.20 |
| CHEMBL5556677 | — | — | 1 | - |
| CHEMBL5557393 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5556102 | — | Ki | = | 1180.0 | nM | 5.93 |
| CHEMBL5557729 | — | Ki | = | 3480.0 | nM | 5.46 |
| CHEMBL5542965 | — | Ki | = | 6280.0 | nM | 5.20 |
| CHEMBL5556677 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL5557393 | — | Ki | - | — | - |