Assay Detail
Functional
CHEMBL5504248
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as activation by measuring beta-arrestin recruitment
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Potent, Selective Agonists for the Cannabinoid-like Orphan G Protein-Coupled Receptor GPR18: A Promising Drug Target for Cancer and Immunity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.59 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL559612 | CP-55940 | — | 1 | 9.00 |
| CHEMBL465 | DRONABINOL | 4.0 | 1 | 8.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL559612 | CP-55940 | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL465 | DRONABINOL | EC50 | = | 6.73 | nM | 8.17 |