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Assay Detail

CHEMBL5505499

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS CoV-2 USA-WA1/2020 infected in African green monkey Vero E6 cells assessed as reduction in viral plaque formation incubated for 3 days by plaque reduction neutralization assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

New Strategies for Responding to SARS-CoV-2: The Present and Future of Dual-Target Drugs.
Zhang W, Xiao L, Li D, Hu Y, Yu W.
J Med Chem (2024) 67 : 11522 -11542
PubMed 38967785 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.07 5.08

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL445177 GINGKOLIC ACID 1 5.08
CHEMBL33778 ANACARDIC ACID 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL445177 GINGKOLIC ACID EC50 = 8300.0 nM 5.08
CHEMBL33778 ANACARDIC ACID EC50 = 9000.0 nM 5.05