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Assay Detail

CHEMBL5505511

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-2 infected in African green monkey Vero cells assessed as inhibition of viral replication measured after 24 hrs post infection by qRT-PCR analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

New Strategies for Responding to SARS-CoV-2: The Present and Future of Dual-Target Drugs.
Zhang W, Xiao L, Li D, Hu Y, Yu W.
J Med Chem (2024) 67 : 11522 -11542
PubMed 38967785 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL273264 NAFAMOSTAT 3.0 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL273264 NAFAMOSTAT EC50 = 10.0 nM 8.00