Assay Detail
Binding
CHEMBL5505736
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ERAP1 (unknown origin) using L-pNA as susbtrate
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Endoplasmic reticulum aminopeptidase 1 (CHEMBL5939) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
ERAP Inhibitors in Autoimmunity and Immuno-Oncology: Medicinal Chemistry Insights.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.16 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5518024 | — | — | 1 | 5.52 |
| CHEMBL5557364 | — | — | 1 | 5.16 |
| CHEMBL83148 | PHENYL(PHENYLSULFONYL)AMINE | — | 1 | 5.05 |
| CHEMBL5517687 | — | — | 1 | 5.05 |
| CHEMBL5518044 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5518024 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL5557364 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL83148 | PHENYL(PHENYLSULFONYL)AMINE | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL5517687 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL5518044 | — | IC50 | = | 10000.0 | nM | 5.00 |