Assay Detail
Binding
CHEMBL5505740
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ERAP1 (unknown origin) using L-AMC as substrate
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Endoplasmic reticulum aminopeptidase 1 (CHEMBL5939) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
ERAP Inhibitors in Autoimmunity and Immuno-Oncology: Medicinal Chemistry Insights.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.26 | 5.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5527891 | — | — | 1 | 5.26 |
| CHEMBL5558123 | — | — | 1 | - |
| CHEMBL5512459 | — | — | 1 | - |
| CHEMBL5555425 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5527891 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL5558123 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5512459 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5555425 | — | IC50 | > | 100000.0 | nM | - |