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Assay Detail

CHEMBL5506099

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Toxoplasma gondii Farnesyl pyrophosphate synthase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Toxoplasma gondii
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

An updated review of chemical compounds with anti-Toxoplasma gondii activity.
Rodriguez JB, Szajnman SH.
Eur J Med Chem (2023) 262 : 115885 -115885
PubMed 37871407 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.82 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5558698 1 7.30
CHEMBL54004 1 6.89
CHEMBL5558207 1 6.77
CHEMBL5567234 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5558698 IC50 = 50.0 nM 7.30
CHEMBL54004 IC50 = 130.0 nM 6.89
CHEMBL5558207 IC50 = 170.0 nM 6.77
CHEMBL5567234 IC50 = 500.0 nM 6.30