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Assay Detail

CHEMBL5506141

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-2 USA-WA1/2020 infected in African green monkey Vero 76 cells assessed as reduction in virus-induced cytopathic effect incubated for 72 hrs by CellTiter-Glo luminescence based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Targeting SARS-CoV-2 entry processes: The promising potential and future of host-targeted small-molecule inhibitors.
Wu A, Shi K, Wang J, Zhang R, Wang Y.
Eur J Med Chem (2024) 263 : 115923 -115923
PubMed 37981443 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.99 5.99

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL92708 CALPEPTIN 1 5.99

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL92708 CALPEPTIN EC50 = 1033.0 nM 5.99