Assay Detail
Functional
CHEMBL5506173
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against SARS-CoV-2 infected in African green monkey Vero E6 at 0.05 MOI assessed as reduction in viral replication incubated for 48 hrs by RT-PCR analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Cell Type | Vero C1008 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Targeting SARS-CoV-2 entry processes: The promising potential and future of host-targeted small-molecule inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.49 | 7.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5523484 | — | — | 1 | 7.71 |
| CHEMBL5557909 | — | — | 1 | 7.62 |
| CHEMBL5568317 | — | — | 1 | 7.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5523484 | — | IC50 | = | 19.5 | nM | 7.71 |
| CHEMBL5557909 | — | IC50 | = | 23.9 | nM | 7.62 |
| CHEMBL5568317 | — | IC50 | = | 73.3 | nM | 7.13 |