Assay Detail
Binding
CHEMBL5506175
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Binding affinity to furin (unknown origin) assessed as inhibition constant
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting SARS-CoV-2 entry processes: The promising potential and future of host-targeted small-molecule inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.73 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4790628 | — | — | 1 | 11.00 |
| CHEMBL403278 | — | — | 1 | 5.51 |
| CHEMBL1191168 | — | — | 1 | 5.48 |
| CHEMBL449045 | — | — | 1 | 4.93 |
| CHEMBL1644904 | 2-(1-PHENYLETHYLIDENE)HYDRAZINECARBOXIMIDAMIDE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4790628 | — | Ki | = | 0.0101 | nM | 11.00 |
| CHEMBL403278 | — | Ki | = | 3100.0 | nM | 5.51 |
| CHEMBL1191168 | — | Ki | = | 3300.0 | nM | 5.48 |
| CHEMBL449045 | — | Ki | = | 11800.0 | nM | 4.93 |
| CHEMBL1644904 | 2-(1-PHENYLETHYLIDENE)HYDRAZINECARBOXIMIDAMIDE | Ki | = | 273000.0 | nM | - |