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Assay Detail

CHEMBL5506262

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Autocuration

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

Exploring the potential of histone demethylase inhibition in multi-therapeutic approaches for cancer treatment.
Li D, Liang H, Wei Y, Xiao H, Peng X, Pan W.
Eur J Med Chem (2024) 264 : 115999 -115999
PubMed 38043489 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.02 6.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3104349 1 6.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3104349 IC50 = 950.0 nM 6.02