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Assay Detail

CHEMBL5507796

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against DENV
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Dengue virus
Confidence 1 — Organism
Curated By Autocuration

Target

Dengue virus (CHEMBL613757)
Type ORGANISM
Organism Dengue virus

Publication

Design, synthesis and biological evaluation of novel 1,2,4a,5-tetrahydro-4H-benzo[b][1,4]oxazino[4,3-d][1,4]oxazine-based AAK1 inhibitors with anti-viral property against SARS-CoV-2.
Mao ND, Xu Y, Che H, Yao X, Gao Y, Wang C, Deng H, Hui Z, Zhang H, Ye XY.
Eur J Med Chem (2024) 268 : 116232 -116232
PubMed 38377825 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.37 7.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4439128 1 7.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4439128 EC50 = 43.0 nM 7.37