Assay Detail
Binding
CHEMBL5508997
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PRMT3 (unknown origin) by AlphaLISA assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Protein arginine N-methyltransferase 3 (CHEMBL5891) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-based discovery of potent CARM1 inhibitors for colorectal cancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.95 | 6.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5558087 | — | — | 1 | 6.31 |
| CHEMBL5562404 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5558087 | — | IC50 | = | 493.0 | nM | 6.31 |
| CHEMBL5562404 | — | IC50 | = | 2637.0 | nM | 5.58 |