Assay Detail
Binding
CHEMBL5509239
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by Fluorescence polarization assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Induced myeloid leukemia cell differentiation protein Mcl-1 (CHEMBL4361) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting Myeloid Leukemia-1 in Cancer Therapy: Advances and Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.76 | 10.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5538127 | — | — | 1 | 10.59 |
| CHEMBL4572199 | — | — | 1 | 8.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5538127 | — | Ki | = | 0.026 | nM | 10.59 |
| CHEMBL4572199 | — | Ki | = | 1.2 | nM | 8.92 |