Assay Detail
Functional
CHEMBL5509255
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Antiproliferative activity against human AMO1 cells assessed as reduction in cell viability
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | AMO1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting Myeloid Leukemia-1 in Cancer Therapy: Advances and Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 8.21 | 9.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5555963 | — | — | 1 | 9.80 |
| CHEMBL5538127 | — | — | 1 | 8.69 |
| CHEMBL4650225 | MURIZATOCLAX | 1.0 | 1 | 7.87 |
| CHEMBL4297482 | AZD-5991 | 1.0 | 1 | 7.64 |
| CHEMBL5542775 | — | — | 1 | 7.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5555963 | — | EC50 | = | 0.16 | nM | 9.80 |
| CHEMBL5538127 | — | EC50 | = | 2.06 | nM | 8.69 |
| CHEMBL4650225 | MURIZATOCLAX | EC50 | = | 13.5 | nM | 7.87 |
| CHEMBL4297482 | AZD-5991 | EC50 | = | 22.9 | nM | 7.64 |
| CHEMBL5542775 | — | EC50 | = | 90.6 | nM | 7.04 |