Assay Detail
Functional
CHEMBL5509257
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MV4-11 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting Myeloid Leukemia-1 in Cancer Therapy: Advances and Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.63 | 8.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5555963 | — | — | 1 | 8.41 |
| CHEMBL5538127 | — | — | 1 | 7.96 |
| CHEMBL4297482 | AZD-5991 | 1.0 | 1 | 7.46 |
| CHEMBL4650225 | MURIZATOCLAX | 1.0 | 1 | 7.36 |
| CHEMBL5542775 | — | — | 1 | 6.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5555963 | — | EC50 | = | 3.91 | nM | 8.41 |
| CHEMBL5538127 | — | EC50 | = | 10.87 | nM | 7.96 |
| CHEMBL4297482 | AZD-5991 | EC50 | = | 34.9 | nM | 7.46 |
| CHEMBL4650225 | MURIZATOCLAX | EC50 | = | 43.6 | nM | 7.36 |
| CHEMBL5542775 | — | EC50 | = | 106.0 | nM | 6.97 |