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Assay Detail

CHEMBL5510202

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of cell growth in human MDA-MB-231 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of a Novel and Potent Cyclin-Dependent Kinase 8/19 (CDK8/19) Inhibitor for the Treatment of Cancer.
Xu J, Qi H, Wang Z, Wang L, Steurer B, Cai X, Liu J, Aliper A, Zhang M, Ren F, Zhavoronkov A, Ding X.
J Med Chem (2024) 67 : 8161 -8171
PubMed 38690856 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5561973 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5561973 IC50 = 40.0 nM 7.40