Assay Detail
Binding
CHEMBL5510210
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK19/CyclinC (unknown origin) incubated for 60 mins in presence of ATP by scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Cyclin-C/Cyclin-dependent kinase 19 (CHEMBL3883323) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Discovery of a Novel and Potent Cyclin-Dependent Kinase 8/19 (CDK8/19) Inhibitor for the Treatment of Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.98 | 7.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4225966 | SEL-120 FREE BASE | 1.0 | 1 | 7.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4225966 | SEL-120 FREE BASE | IC50 | = | 10.4 | nM | 7.98 |