Assay Detail
Binding
CHEMBL5511147
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Binding affinity to truncated AMPK (unknown origin) assessed as dissociation constant by CD analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
AMP-activated protein kinase, AMPK (CHEMBL2096907) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Homo sapiens |
Publication
Discovery of Oral AMP-Activated Protein Kinase Activators for Treating Hyperlipidemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.75 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL752 | ADENOSINE PHOSPHATE | 4.0 | 1 | 6.82 |
| CHEMBL5557642 | — | — | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL752 | ADENOSINE PHOSPHATE | Kd | = | 150.0 | nM | 6.82 |
| CHEMBL5557642 | — | Kd | = | 210.0 | nM | 6.68 |