Assay Detail
Binding
CHEMBL5512969
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse recombinant VEGFR2 (785 to 1367 residues) in presence of ATP by HTRF assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL3337) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Unlocking the synthetic approaches and clinical application of approved small-molecule drugs for gastrointestinal cancer treatment: A comprehensive exploration.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.38 | 8.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1946170 | REGORAFENIB | 4.0 | 1 | 8.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1946170 | REGORAFENIB | IC50 | = | 4.2 | nM | 8.38 |