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Assay Detail

CHEMBL5513258

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Functional
Antiproliferative activity against human NCI-H1299 cells assessed as reduction in cell viability measured after 72 hrs by AlamarBlue assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-H1299
Confidence 1 — Organism
Curated By Autocuration

Target

NCI-H1299 (CHEMBL612255)
Type CELL-LINE
Organism Homo sapiens

Publication

Therapeutic potential of targeting polo-like kinase 4.
Lei Q, Yu Q, Yang N, Xiao Z, Song C, Zhang R, Yang S, Liu Z, Deng H.
Eur J Med Chem (2024) 265 : 116115 -116115
PubMed 38199166 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.30 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2407901 1 8.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2407901 IC50 = 5.0 nM 8.30