Assay Detail
Binding
CHEMBL5513307
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant CDK9 (773 to 928 residues) expressed in insect cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Insect cell |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Drug discovery and optimization based on the co-crystal structure of natural product with target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.58 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL380500 | VARIOLIN B | — | 1 | 7.58 |
| CHEMBL4740353 | — | — | 1 | 7.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL380500 | VARIOLIN B | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL4740353 | — | IC50 | = | 26.0 | nM | 7.58 |