Assay Detail
Binding
CHEMBL5513331
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human MMP13 catalytic domain (Tyr104 to Asp270 residues) using acetyl-Pro-Leu-Gly-[2-mercapto-4-methyl-pentanoyl]-Leu-Gly-O-ethyl ester as substrate by absorbance based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of matrix metalloproteinase inhibitors as anti-skin photoaging agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.35 | 9.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL496942 | — | — | 1 | 9.17 |
| CHEMBL409536 | — | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL496942 | — | IC50 | = | 0.67 | nM | 9.17 |
| CHEMBL409536 | — | IC50 | = | 30.0 | nM | 7.52 |