Assay Detail

CHEMBL5513508

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiproliferative activity against human A549 cells assessed as reduction in cell viability by MTT assay

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

A549 (CHEMBL392) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

A549 (CHEMBL392) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target A549

CHEMBL392

Anchored from Assay target.

Protein identity A549

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	A549
Confidence	1 — Organism
Curated By	Autocuration

Target

A549 (CHEMBL392) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Targeting autophagy drug discovery: Targets, indications and development trends.

Jiang M, Wu W, Xiong Z, Yu X, Ye Z, Wu Z.
Eur J Med Chem (2024) 267 : 116117 -116117
PubMed 38295689 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.52	8.52

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2107830	EMPAGLIFLOZIN	4.0	1	8.52

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2107830	EMPAGLIFLOZIN	EC50	=	3.0	nM	8.52