Assay Detail
Binding
CHEMBL5513510
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ATGL ubiquitination in human HepG2 cells assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Patatin-like phospholipase domain-containing protein 2 (CHEMBL3822353) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting autophagy drug discovery: Targets, indications and development trends.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.14 | 10.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2048872 | — | — | 1 | 10.77 |
| CHEMBL464529 | NUCIFERINE | — | 1 | 7.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2048872 | — | Ki | = | 0.017 | nM | 10.77 |
| CHEMBL464529 | NUCIFERINE | Ki | = | 31.0 | nM | 7.51 |