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Assay Detail

CHEMBL5513615

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of His6-tagged Max (151 residues)(unknown origin) expressed in bacterial system/recombinant MYC ) (unknown origin) expressed in bacterial system by EMSA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

c-Myc/Max (CHEMBL3301395)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

MYC the oncogene from hell: Novel opportunities for cancer therapy.
Papadimitropoulou A, Makri M, Zoidis G.
Eur J Med Chem (2024) 267 : 116194 -116194
PubMed 38340508 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.48 4.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1336889 1 4.48
CHEMBL4286890 1 4.47
CHEMBL2312756 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1336889 IC50 = 33000.0 nM 4.48
CHEMBL4286890 IC50 = 34000.0 nM 4.47
CHEMBL2312756 IC50 = 146000.0 nM -