Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5514299

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human WM9 cells assessed as inhibition of cell growth incubated for 72 hrs by XTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type WM9
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Unlocking the potential of 1,4-naphthoquinones: A comprehensive review of their anticancer properties.
Angulo-Elizari E, Henriquez-Figuereo A, Morán-Serradilla C, Plano D, Sanmartín C.
Eur J Med Chem (2024) 268 : 116249 -116249
PubMed 38458106 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.85 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5543019 1 6.22
CHEMBL5191461 1 5.82
CHEMBL5205851 1 5.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5543019 IC50 = 600.0 nM 6.22
CHEMBL5191461 IC50 = 1500.0 nM 5.82
CHEMBL5205851 IC50 = 3200.0 nM 5.50