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Assay Detail

CHEMBL5514441

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MCF7 cells incubated for 7 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Unlocking the potential of 1,4-naphthoquinones: A comprehensive review of their anticancer properties.
Angulo-Elizari E, Henriquez-Figuereo A, Morán-Serradilla C, Plano D, Sanmartín C.
Eur J Med Chem (2024) 268 : 116249 -116249
PubMed 38458106 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL295316 PLUMBAGIN 1.0 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL295316 PLUMBAGIN IC50 = 1000.0 nM 6.00