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Assay Detail

CHEMBL5515845

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DNA polymerase beta (unknown origin) measured after 30 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA polymerase beta (CHEMBL2392)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update.
Hillebrand L, Liang XJ, Serafim RAM, Gehringer M.
J Med Chem (2024) 67 : 7668 -7758
PubMed 38711345 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.69 6.69

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5557939 1 6.69

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5557939 IC50 = 204.0 nM 6.69