Assay Detail
Functional
CHEMBL5516418
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Antibacterial activity against Micrococcus luteus assessed as reduction in bacterial cell viability incubated for 24 hrs by nutrient agar plate method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Micrococcus luteus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Secondary Structure Stabilization of Macrocyclic Antimicrobial Peptides via Cross-Link Swapping.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.13 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL174 | AMPICILLIN | 4.0 | 1 | 5.96 |
| CHEMBL5558688 | — | — | 1 | 5.08 |
| CHEMBL5568536 | — | — | 1 | 4.96 |
| CHEMBL5556492 | — | — | 1 | 4.91 |
| CHEMBL5556572 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL174 | AMPICILLIN | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL5558688 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL5568536 | — | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL5556492 | — | IC50 | = | 12300.0 | nM | 4.91 |
| CHEMBL5556572 | — | IC50 | = | 18000.0 | nM | 4.75 |