Assay Detail
Functional
CHEMBL5517433
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against SARS-CoV-2 infected in Vero E6 cells assessed as reduction in viral RNA copy number measured after 48 hrs by qRT-PCR analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Cell Type | Vero E6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Colloidal Aggregation Confounds Cell-Based Covid-19 Antiviral Screens.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.39 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1214598 | UMIFENOVIR | 3.0 | 1 | 5.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1214598 | UMIFENOVIR | EC50 | = | 4110.0 | nM | 5.39 |