Assay Detail
Functional
CHEMBL5517519
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human P2Y6R stably expressed in UDP-stimulated HEK293 cells incubated for 0.5 hrs by IP3 production assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of N-Substituted Acetamide Derivatives as Promising P2Y<sub>14</sub>R Antagonists Using Molecular Hybridization Based on Crystallographic Overlay.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.05 | 4.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5557370 | — | — | 1 | 4.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5557370 | — | IC50 | = | 89700.0 | nM | 4.05 |