Assay Detail
Binding
CHEMBL5518256
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Inhibition of HIV-1 RNA-dependent RNA polymerase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent advances on dual inhibitors targeting HIV reverse transcriptase associated polymerase and ribonuclease H.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.03 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1958265 | — | — | 1 | 5.85 |
| CHEMBL5560779 | — | — | 1 | 5.40 |
| CHEMBL5557831 | — | — | 1 | 5.10 |
| CHEMBL4211455 | — | — | 1 | 4.92 |
| CHEMBL5557278 | — | — | 1 | 4.79 |
| CHEMBL55814 | ATHRAQUINONES A | — | 1 | 4.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1958265 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL5560779 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL5557831 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL4211455 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL5557278 | — | IC50 | = | 16100.0 | nM | 4.79 |
| CHEMBL55814 | ATHRAQUINONES A | IC50 | = | 79000.0 | nM | 4.10 |