Assay Detail
Binding
CHEMBL5518283
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NAMPT (unknown origin) using NAM as substrate pre-treated for 15 mins followed by substrate addition incubated for 60 mins by fluorescence based microplate reader analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Nicotinamide phosphoribosyltransferase (CHEMBL1744525) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent advances of targeting nicotinamide phosphoribosyltransferase (NAMPT) for cancer drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.41 | 8.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3127521 | — | — | 1 | 8.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3127521 | — | IC50 | = | 3.9 | nM | 8.41 |