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Assay Detail

CHEMBL5518405

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human TRPV1 expressed in HEK293 cells assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Progress in the development of TRPV1 small-molecule antagonists: Novel Strategies for pain management.
Zhu K, Wang L, Liao T, Li W, Zhou J, You Y, Shi J.
Eur J Med Chem (2023) 261 : 115806 -115806
PubMed 37713804 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.70 9.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2177429 1 9.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2177429 Ki = 0.2 nM 9.70