Assay Detail
Functional
CHEMBL5519059
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human CL97 cells harboring mutated EGFR assessed as inhibition of cell growth by SRB assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CL97 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dual-targeting compounds possessing enhanced anticancer activity via microtubule disruption and histone deacetylase inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.62 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5567219 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5567219 | — | IC50 | = | 240.0 | nM | 6.62 |