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Assay Detail

CHEMBL5522717

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FABP5 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Fatty acid-binding protein 5 (CHEMBL3674)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent Advances on Small-Molecule Inhibitors of Lipocalin-like Proteins.
Chen S, Pan Z, Liu M, Guo L, Jiang X, He G.
J Med Chem (2024) 67 : 5144 -5167
PubMed 38525852 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.86 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL185595 1 6.24
CHEMBL363032 1 5.96
CHEMBL364141 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL185595 IC50 = 570.0 nM 6.24
CHEMBL363032 IC50 = 1100.0 nM 5.96
CHEMBL364141 IC50 = 4300.0 nM 5.37