Assay Detail
Functional
CHEMBL5523085
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Antiproliferative activity against human LN-18 cells assessed as inhibition of cell growth incubated for 72 hrs MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LN-18 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of an Imidazopyridazine-Based MNK1/2 Inhibitor for the Treatment of Lymphoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.62 | 6.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5559028 | — | — | 1 | 6.04 |
| CHEMBL4073443 | TOMIVOSERTIB | 2.0 | 1 | 5.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5559028 | — | IC50 | = | 910.0 | nM | 6.04 |
| CHEMBL4073443 | TOMIVOSERTIB | IC50 | = | 6270.0 | nM | 5.20 |