Assay Detail
Functional
CHEMBL5523876
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against TBEV infected in human A549 cells assessed as reduction in cytopathic effect pretreated with cells for 1 hr followed by viral infection and measured after 3 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Tick-borne encephalitis virus |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Tick-borne encephalitis virus (CHEMBL4296604) ↗| Type | ORGANISM |
| Organism | Tick-borne encephalitis virus |
Publication
Elongation of N<sup>6</sup>-benzyladenosine scaffold via Pd-catalyzed C-C bond formation leads to derivatives with antiflaviviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1630221 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1630221 | — | EC50 | = | 200.0 | nM | 6.70 |