Assay Detail
Functional
CHEMBL5523877
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against TBEV infected in porcine PS cells assessed as r inhibition of virus induced cytopathic effect pretreated with cells for 24 hrs followed by viral infection for 24 hrs and measured after 72 hrs post infection
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Tick-borne encephalitis virus |
| Cell Type | PS |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Tick-borne encephalitis virus (CHEMBL4296604) ↗| Type | ORGANISM |
| Organism | Tick-borne encephalitis virus |
Publication
Elongation of N<sup>6</sup>-benzyladenosine scaffold via Pd-catalyzed C-C bond formation leads to derivatives with antiflaviviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.80 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL72928 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL72928 | — | EC50 | = | 1600.0 | nM | 5.80 |