Assay Detail
Binding
CHEMBL5524616
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CPT1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Carnitine O-palmitoyltransferase 1, liver isoform (CHEMBL1293194) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Modulators for palmitoylation of proteins and small molecules.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.57 | 6.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1231506 | TEGLICAR | 2.0 | 1 | 6.17 |
| CHEMBL1232077 | OXFENICINE | 2.0 | 1 | 4.96 |
| CHEMBL633 | AMIODARONE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1231506 | TEGLICAR | IC50 | = | 680.0 | nM | 6.17 |
| CHEMBL1232077 | OXFENICINE | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL633 | AMIODARONE | IC50 | = | 228000.0 | nM | - |