Assay Detail
Binding
CHEMBL5524732
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Agonist activity at rat mGlu4 R258Q/D262/R263 mutant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel Inhibitory Site Revealed by <b>XAP044</b> Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.06 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3114673 | — | — | 1 | 5.16 |
| CHEMBL33567 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3114673 | — | EC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL33567 | — | EC50 | = | 11100.0 | nM | 4.96 |