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Assay Detail

CHEMBL5526372

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Induction of DNA (unknown origin) minor groove alkylation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Target

DNA (CHEMBL2311221)
Type NUCLEIC-ACID
Organism Homo sapiens

Publication

Recent Advances in Targeted Cancer Therapy: Are PDCs the Next Generation of ADCs?
Zhang B, Wang M, Sun L, Liu J, Yin L, Xia M, Zhang L, Liu X, Cheng Y.
J Med Chem (2024) 67 : 11469 -11487
PubMed 38980167 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.40 10.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5564686 1 10.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5564686 IC50 = 0.04 nM 10.40