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Assay Detail

CHEMBL5527155

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of MAO-A (unknown origin) measured by MAO-GloTM method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] A (CHEMBL1951)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Natural Product-Inspired Dopamine Receptor Ligands.
Dorogan M, Namballa HK, Harding WW.
J Med Chem (2024) 67 : 12463 -12484
PubMed 39038276 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.56 5.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL151 LUTEOLIN 2.0 1 5.07
CHEMBL228430 1 4.05
CHEMBL470234 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL151 LUTEOLIN IC50 = 8570.0 nM 5.07
CHEMBL228430 IC50 = 89310.0 nM 4.05
CHEMBL470234 IC50 = 204940.0 nM -